Author
Abstract
Considering the importance of rapid determination of
antibacterial susceptibility of bacteria, isolated from infectious diseases for the selection of appropriate
therapy as soon as possible and increasing the success of therapy, decreasing unnecessary use of antibacterial
agents and side-effects, and lowers the overall healthcare costs.We have designed and evaluated a rapid
antibacterial susceptibility medium which is based on a rapid colorimetric medium that
indicates growth by changing its color. In this study, we have
assessed antibacterial susceptibility patterns of non-fermentative bacteria and
Enterobacteriaceae isolated from clinical samples by rapid colorimetric medium according to standard CLSI method. Colorimetric medium proved to be
a reliable rapid test for determining antibacterial susceptibility testing,
between two methods total agreement was 92.93% for Entrobacteriacea and 90.46%
for non-fermentative bacteria. Major discrepancy was 3.28 % for
non-fermentative bacteria and 3.52% for Enterobacreiacea. Colorimetric medium
makes results available between 6-8 hours. It can be considered as a novel and
reliable quick method for the assessing of bacterial susceptibility to
antibiotics.
Keywords
)